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Anaphylaxis, or syok anafilaksis, is a severe and potentially life-threatening allergic reaction that requires immediate medical attention. Prompt recognition and treatment with epinephrine and supportive care can save lives. Prevention involves avoidance of allergens, development of an emergency plan, and carrying an EpiPen.

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Anaphylaxis is a systemic allergic reaction that involves multiple organ systems. It is characterized by the rapid release of histamine and other mediators from mast cells, leading to vasodilation, increased permeability, and smooth muscle contraction. According to the World Health Organization (WHO), anaphylaxis affects approximately 1-2% of the general population, with a mortality rate of 0.5-1.5 per 100,000 person-years. syok anafilaksis pdf

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