David Gene Best ✦

The DAVID gene is inherited in an autosomal dominant pattern, meaning that a single copy of the mutated gene is enough to cause the condition. However, most cases of CD19-related diseases are sporadic, meaning that they occur randomly and are not inherited from a parent.

The DAVID gene provides instructions for making the CD19 protein, which is involved in the activation and regulation of B cells. CD19 is a receptor that helps to regulate B cell development, activation, and antibody production. It works by interacting with other molecules on the surface of B cells, such as CD21 (CR2) and CD81 (TAPA-1), to activate signaling pathways that control B cell growth and differentiation. david gene