Gen V is essentially a college drama on steroids (literally, Compound V). Set at Godolkin University (God U), the premier school for Supes, the series follows Marie Moreau (Jaz Sinclair), a blood-manipulator with a tragic past, as she navigates the social hierarchy of superhero education. The school is a pressure cooker where academic success is measured by public approval ratings and corporate marketability rather than GPA.

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The ensemble cast is the show’s strongest asset. Unlike the often one-dimensional "Supe of the week" victims in the parent series, the students of God U are given nuanced arcs.