These formats use "inter-frame compression." To show you one frame, your computer has to look at the frame before it, and the frame before that. It’s like trying to read a book where every page only tells you what changed from the previous page. It makes your CPU scream.
A balanced high-quality editing codec offering nearly all the benefits of ProRes 422 HQ but at a reduced data rate. 4:2:2 Color Depth: 10-bit .prores