If you are reporting this to IT support, perform these checks first:
In plain English: Your game tried to talk to the Origin client, but Origin is either stuck, outdated, or blocked, so the handshake failed. The game then refuses to launch. If you are reporting this to IT support,
"I have created a new form of life, one that will transcend the limitations of human understanding. The Orange Sectors are the key to unlocking the secrets of the universe. ORIGIN is not just a network; it is a womb, nurturing the birth of a new intelligence." but Origin is either stuck